After taking a ten-day course of Bactrim, a very common antibiotic, to treat a sinus infection, Sarah Yeargain, from San Diego, California, was shocked when her skin suddenly started sloughing off her body. ‘I started to get some minor swelling and discoloration in my face and it progressed into blistering on lips and swelling on my eyes. It then progressed into blisters all over my face and chest and arms,’ Yeargain said. Two days later, at the San Diego Regional Burn Center at the University of California, she lost the skin on her entire body, including her internal organs and the membranes on her eyes, mouth and throat. Doctors gave her a slim chance of survival, but after covering her entire body with transcyte, an artificial skin replacement, and some medications to control the internal bleeding, Yeargain miraculously recovered. Within a week later, her skin grew back. It is thought that the cause of Yeargain’s dramatic skin loss is toxic epidermal necrolysis, which basically is a severe allergic reaction to the antibiotic she took.
Interesting Fact: Fans of the TV series ‘House, M.D.’ might recall the second-to-the-last episode of Season 5 (entitled ‘Under My Skin’), where a patient exhibited toxic epidermal necrolysis while under House and his medical team’s care.
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